@Rene have you lost weight? I had a bottle sent to my adult daughter in Alaska and I’m worried because it takes so long to ship anything to Alaska and it came already reconstituted, which would’ve been better if it came unconstituted like it used to, for me. Then we wouldn’t have to worry about it Going bad in a six day shipping process. She injected on Saturday and is not noticing anything. In the first time I started, I noticed the same day although it wasn’t from this company it was from a pharmacy.